Antifungal macrocyclic polylactones from Penicillium verruculosum.

نویسندگان

  • J Breinholt
  • G W Jensen
  • R I Nielsen
  • C E Olsen
  • J C Frisvad
چکیده

Three macrocyclic polylactones have been isolated from Penicillium verruculosum. Two were found to be novel and the third to be identical with NG-012(1). Their structures were elucidated by spectroscopic and chemical methods. A full assignment of 1H- and 13C-resonances in acetone-d6 are given for all three compounds. The compounds show antifungal activity.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 46 7  شماره 

صفحات  -

تاریخ انتشار 1993